A significant amount of effort has been dedicated by EFPIA members to develop in-house training material in the form of easily accessible tools that provide assessments early on in the drug discovery process and highlight potential sustainability issues. Reagent selection guides assist the user in selecting the ‘greenest’ reagent for a particular transformation. Whilst it is important to have a sound understanding of issues and the wider implications surrounding the reagents you use in your research, it is not necessarily practical to spend significant amounts of time analysing each individual substance. One of the advantages of using selection guides is that the data collection and analysis has already been performed. The individual ranking or grouping within the guides allows you to make an informed decision as to the most appropriate choice for your needs.
By the end of this module you should:
- Understand why reagent selection guides are needed in the pharmaceutical industry;
- Be able to describe the criteria used in devising such guides, and the resulting benefits and limitations;
- Be aware of the use of these guides in practice via specific case studies.