Dependence on crude oil
The use of crude oil as a carbon feedstock for the manufacture of chemicals has dominated the industry with few exceptions, for example a small percentage of naturally-derived compounds (e.g. for use in personal care products and pharmaceuticals).  In this video Dr Tom Farmer at the Green Chemistry Centre of Excellence, University of York outlines where our dependence on crude oil derives from.
- Green and Sustainable Chemistry: An Introduction, in Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, The Royal Society of Chemistry, 2016, ch. 1, pp. 1-11. ,